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              <text>Simon Hofman&lt;br /&gt;Laurian Hafkemeijer&lt;br /&gt;Ad de Jongh&lt;br /&gt;Annemieke Starrenburg&lt;br /&gt;Karin Slotema</text>
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              <text>&lt;a href="https://doi.org/10.1186/s13063-022-06082-6"&gt;https://doi.org/10.1186/s13063-022-06082-6&lt;/a&gt;</text>
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              <text>Hofman, S., Hafkemeijer, L., de Jongh, A., Starrenburg, A., &amp;amp; Slotema. K. (2022). &lt;a href="https://doi.org/10.1186/s13063-022-06082-6"&gt;Trauma-focused EMDR for personality disorders among outpatients (TEMPO): study protocol for a multi-centre, single-blind, randomized controlled trial.&lt;/a&gt; Trials, 23(196). doi:10.1186/s13063-022-06082-6</text>
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                <text>Trauma-focused EMDR for personality disorders among outpatients (TEMPO): study protocol for a multi-centre, single-blind, randomized controlled trial</text>
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                <text>&lt;strong&gt;Background&lt;/strong&gt;&lt;br /&gt;Existing recommended treatment options for personality disorders (PDs) are extensive and costly. There is emerging evidence indicating that trauma-focused treatment using eye movement desensitization and reprocessing (EMDR) therapy aimed at resolving memories of individuals’ adverse events can be beneficial for this target group within a relatively short time frame. The primary purpose of the present study is to determine the effectiveness of EMDR therapy versus waiting list in reducing PD symptom severity. Furthermore, the effects of EMDR therapy on trauma symptom severity, loss of diagnosis, personal functioning, quality of life, and mental health outcomes will be determined. In addition, the cost-effectiveness of EMDR therapy in the treatment of PDs is investigated. Moreover, predictors of treatment success, symptom deterioration and treatment discontinuation will be assessed. Lastly, experiences with EMDR therapy will be explored. &lt;br /&gt;&lt;br /&gt;&lt;strong&gt;Method&lt;/strong&gt;&lt;br /&gt;In total, 159 patients with a PD will be included in a large multicentre single-blind randomized controlled trial. The Structured Clinical Interview for DSM-5 Personality Disorders will be used to determine the presence of a PD. Participants will be allocated to either a treatment condition with EMDR therapy (ten biweekly 90-min sessions) or a waiting list. Three months after potential treatment with EMDR therapy, patients can receive treatment as usual for their PD. All participants are subject to single-blinded baseline, post-intervention and 3-, 6- and 12-month follow-up assessments. The primary outcome measures are the Assessment of DSM-IV Personality Disorders and the Clinician-Administered PTSD Scale for DSM-5. For cost-effectiveness, the Treatment Inventory of Costs in Patients with psychiatric disorders, EuroQol-5D-3L, and the Mental Health Quality of Life Questionnaire will be administered. The PTSD Checklist for DSM-5, Brief State Paranoia Checklist and Difficulties in Emotion Regulation Scale will be used to further index trauma symptom severity. Type of trauma is identified at baseline with the Childhood Trauma Questionnaire-SF and Life Events Checklist for the DSM-5. Personal functioning and health outcome are assessed with the Level of Personality Functioning Scale-BF 2.0, Outcome Questionnaire-45 and Mental Health Quality of Life Questionnaire. Experiences with EMDR therapy of patients in the EMDR therapy condition are explored with a semistructured interview at post-intervention. &lt;br /&gt;&lt;br /&gt;&lt;strong&gt;Discussion&lt;/strong&gt;&lt;br /&gt;It is expected that the results of this study will contribute to knowledge about the effectiveness, and cost-effectiveness of trauma-focused treatment using EMDR therapy in individuals diagnosed with a PD. Follow-up data provide documentation of long-term effects of EMDR therapy on various outcome variables, most importantly the reduction of PD symptom severity and loss of diagnoses. &lt;br /&gt;&lt;br /&gt;&lt;strong&gt;Trial registration&lt;/strong&gt;&lt;br /&gt;Netherlands Trial Register NL9078. Registered on 31 November 2020 &lt;br /&gt;&lt;br /&gt;&lt;br /&gt;Keywords: EMDR, Personality disorder, Trauma, Effectiveness, Cost-effectiveness, Economic evaluation, Predictors, Treatment experiences, Study protocol, Randomized controlled trial</text>
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                <text>Trials, 23(196). doi:10.1186/s13063-022-06082-6</text>
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                <text>2022</text>
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        <name>Cost-Effectiveness</name>
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              <text>Paul A. J. M. de Bont&lt;br /&gt;Berber M. van der Vleugel&lt;br /&gt;David P. G. van den Berg&lt;br /&gt;Carlijn de Roos&lt;br /&gt;Joran Lokkerbol&lt;br /&gt;Filip Smit&lt;br /&gt;Ad de Jongh&lt;br /&gt;Mark van der Gaag&lt;br /&gt;Agnes van Minnen</text>
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              <text>de Bont, P. A. J. M., van der Vleugel, B. M., van den Berg, D. P. G., de Roos, C., Lokkerbol, J., Smit, F., de Jongh, A., van der Gaag, M., &amp;amp; van Minnen, A. (2019, January). &lt;a href="https://doi.org/10.1080/20008198.2018.1565032"&gt;Health-economic benefits of treating trauma in psychosis.&lt;/a&gt; European Journal Of Psychotraumatology, 10(1). doi:10.1080/20008198.2018.1565032.</text>
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              <text>&lt;a href="https://doi.org/10.1080/20008198.2018.1565032"&gt;https://doi.org/10.1080/20008198.2018.1565032&lt;/a&gt;</text>
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                <text>Health-economic benefits of treating trauma in psychosis</text>
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                <text>&lt;strong&gt;Background:&lt;/strong&gt; &lt;br /&gt;Co-occurrence of posttraumatic stress disorder (PTSD) in psychosis (estimated as 12%) raises personal suffering and societal costs. Health-economic studies on PTSD treatments in patients with a diagnosis of a psychotic disorder have not yet been conducted, but are needed for guideline development and implementation. This study aims to analyse the cost-effectiveness of guideline PTSD therapies in patients with a psychotic disorder. &lt;br /&gt;&lt;br /&gt;&lt;strong&gt;Methods:&lt;/strong&gt; &lt;br /&gt;This health-economic evaluation alongside a randomized controlled trial included 155 patients with a psychotic disorder in care as usual (CAU), with comorbid PTSD. Participants received eye movement desensitization and reprocessing (EMDR) (n = 55), prolonged exposure (PE) (n = 53) or waiting list (WL) (n = 47) with masked assessments at baseline (T0) and at the two-month (post-treatment, T2) and six-month follow-up (T6). Costs were calculated using the TiC-P interview for assessing healthcare consumption and productivity losses. Incremental cost-effectiveness ratios and economic acceptability were calculated for quality-adjusted life years (EQ-5D-3L-based QALYs) and PTSD 'Loss of diagnosis' (LoD, CAPS). &lt;br /&gt;&lt;br /&gt;&lt;strong&gt;Results:&lt;/strong&gt; &lt;br /&gt;Compared to WL, costs were lower in EMDR (-€1410) and PE (-€501) per patient per six months. In addition, EMDR (robust SE 0.024, t = 2.14, p = .035) and PE (robust SE 0.024, t = 2.14, p = .035) yielded a 0.052 and 0.051 incremental QALY gain, respectively, as well as 26% greater probability for LoD following EMDR (robust SE = 0.096, z = 2.66, p = .008) and 22% following PE (robust SE 0.098, z = 2.28, p = .023). Acceptability curves indicate high probabilities of PTSD treatments being the better economic choice. Sensitivity analyses corroborated these outcomes. &lt;br /&gt;&lt;br /&gt;&lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;br /&gt;Adding PTSD treatment to CAU for individuals with psychosis and PTSD seem to yield better health and less PTSD at lower costs, which argues for implementation..</text>
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                <text>European Journal Of Psychotraumatology, 10(1). doi:10.1080/20008198.2018.1565032.</text>
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