舍曲林联合EMDR治疗抑郁症对照研究 Sertraline treatment of depression combined EMDR research: A control study of sertraline combined with the EMDR in the treatment of depression

目的 探讨舍曲林联合眼动脱敏和再加工治疗对抑郁症的临床疗效及安全性.方法 将64例抑郁症患者随机分为两组各32例,均给予舍曲林治疗,研究组联合眼动脱敏和再加工治疗,疗程均为6w.于治疗前及治疗第1 w、2 w、6 w末采用汉密顿抑郁量表、临床总体印象量表评定临床疗效,副反应量表评定不良反应.结果 治疗6 w末研究组有效率87.5%,对照组为84.4%,两组差异无显著性(χ2=0.129,P＞0.05).汉密顿抑郁量表、临床总体印象量表评分,研究组治疗1 w末均较对照组下降显著(P均＜0.05),2 w末均较对照组下降极显著(P均＜0.01),6 w末差异均无显著性(P均＞0.05).两组不良反应均轻微(P＞0.05).结论 舍曲林联合眼动脱敏和再加工治疗治疗抑郁症疗效显著,起效更快,安全性高,依从性好.

Objective: To study the combined sertraline and reprocessing eye movement desensitization treatment for depression efficacy and safety. Methods 64 patients with depression were randomly divided into two groups, 32 cases were treated with sertraline treatment, the joint study group eyes Activity desensitization and reprocessing therapy, a course of 6w. in the first before treatment and 1 w, 2 w, 6 w end with Hamilton Depression Rating Scale, Clinical Global Impression Scale for assessment of clinical efficacy, adverse side effects rating scale reaction. Results 6 w end of study group and 87.5%, 84.4% of the control group, no significant difference between the two groups (χ2 = 0.129, P> 0.05). Hamilton Depression Rating Scale, Clinical Global Impression Scale scores 1 w at the end of treatment group was significantly decreased compared with the control group (P all 0.05) . two adverse reactions were mild (P> 0.05). Conclusion Joint eye sertraline desensitization and reprocessing therapy treatment of depression a significant effect, faster onset, high safety, good compliance.

Journal

Chinese

Song Lei
Wang Zhen-Ying

Lei, S., & Zhen-Yin, W. (2007, November). [Sertraline treatment of depression combined EMDR research: A control study of sertraline combined with the EMDR in the treatment of depression]. Journal of Clinical Psychosomatic Disease, 13(4). doi:10.3969/j.issn.1672-187X.2007.04.008. Chinese