Randomized controlled trial on the ASSYST treatment intervention with female children polytraumatized by adverse childhood experiences, neglect, and maltreatment
Description
The aim of this randomized controlled trial with an intention-to-treat analysis was to evaluate the effectiveness, efficacy, and safety of the Acute Stress Syndrome Stabilization Individual (ASSYST-I) treatment intervention in reducing posttraumatic stress disorder (PTSD) symptoms in female children polytraumatized by adverse childhood experiences, neglect, and maltreatment. A total of 40 female children met the inclusion criteria and participated in the study. Participants’ ages ranged from 8 to 17 years old (M =14.67 years). A two-arm randomized controlled trial (RCT) design was applied. PTSD symptoms were measured in three-time points for all participants in the study. Results showed that the intervention had a significant effect for time on PTSD symptoms (F (2,76) = 36.92 p <.000, η² = .493). A significant effect for group was also found (F (1, 38 = 32.7, p<.005, η² = .896) with a large effect, and a significant interaction between time and group, (F (2, 76) = 56.00, p <.000, η² = .600). Means comparison using t test between groups showed significant differences between the Treatment Group (TG) and the Control Group (CG) in the three-time points comparisons showing a large effect on Time 2 (Post-treatment assessment) which was maintained on Time 3 (Follow-up assessment). Results on the Reliable Change Index (RCI) and the Clinically Significant Change (CSC) Margin showed that the ASSYST-I treatment intervention exhibited reliable change on PTSD symptom reduction and clinically significant change, indicating that the treatment group participants are more likely to belong to the non-PTSD population after the intervention. Conversely, the control group participants are more likely to belong to the PTSD population. No adverse effects or events were reported by the participants during the treatment procedure administration or at follow-up. None of the participants showed clinically significant worsening/exacerbation of symptoms after treatment. Participants in the control group received the intervention treatment after the follow-up assessment, fulfilling our ethical criteria.
Format
Journal
Language
English
Original Work Citation
Carretero, K, P., Delgadillo, A., Villarreal, A. M., Roque, J. P., Poiré, A., Mainthow, N., Givaudan, M., & Jarero, I. (2023, July). Randomized controlled trial on the ASSYST treatment intervention with female children polytraumatized by adverse childhood experiences, neglect, and maltreatment.
Citation
“Randomized controlled trial on the ASSYST treatment intervention with female children polytraumatized by adverse childhood experiences, neglect, and maltreatment,” Francine Shapiro Library, accessed May 10, 2024, https://francineshapirolibrary.omeka.net/items/show/28505.